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Spironolactone for the treatment of congestive heart failure in dogs.

Prilactone Vet Brochure.pdf


  • Prilactone contains sprinolactone and is licensed for the treatment of congestive heart failure caused by valvular regurgitation in dogs, in combination with standard therapy (including diuretic support where necessary)
  • Prilactone is an aldosterone antagonist and thereby protects against the harmful effects of aldosterone, which include myocardial fibrosis1

1 – Ovaert P. et al. (2010), Aldosterone receptor antagonists – how cardiovascular actions may explain their beneficial effects in heart failure, Journal of Veterinary Pharmacology and Therapeutics, 33(2), 109 - 117

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